Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 6/20 | 0.34 |
| ▸ | CCND1 | P24385 | 5/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.34 |
| ▸ | CCND3 | P30281 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650828 | 0.91 | CDK4 (0.33) | CDK4CCND1CDK6CCND3EGFR | |
| SCHEMBL22650586 | 0.89 | EGFR (0.39) | CDK4CCND1CDK6CCND3EGFR | |
| SCHEMBL22650827 | 0.81 | CDK4 (0.39) | CDK4CCND1CDK6CCND3EGFR | |
| SCHEMBL22650358 | 0.78 | EGFR (0.33) | CDK4CCND1CDK6CCND3EGFR | |
| SCHEMBL22650743 | 0.76 | DAPK1 (0.33) | CDK4CCND1EGFRCDK1CCNB1 | |
| SCHEMBL29491180 | 0.76 | DAPK1 (0.33) | CDK4CCND1EGFRCDK1CCNB1 | |
| SCHEMBL22650826 | 0.76 | AAK1 (0.38) | CDK4CCND1CDK6CCND3EGFR | |
| SCHEMBL19836706 | 0.74 | CDK4 (0.54) | CDK4CCND1CDK6CCND3EGFR | |
| SCHEMBL20987199 | 0.71 | CDK4 (0.53) | CDK4CCND1CDK6CCND3EGFR | |
| SCHEMBL30309451 | 0.71 | CDK4 (0.53) | CDK4CCND1CDK6CCND3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |