Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | ESRRA | P11474 | 2/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | RARG | P13631 | 2/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841190 | 0.88 | TSHR (0.67) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL10428428 | 0.87 | NR1H4 (0.48) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL2773345 | 0.84 | RARA (0.61) | TSHRALDH1A1GAAESRRARARA | |
| SCHEMBL13424093 | 0.82 | ESRRA (0.42) | TSHRALDH1A1GAANR1H4ESRRA | |
| SCHEMBL7570534 | 0.81 | KDM4E (0.53) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL9247660 | 0.81 | NR1H4 (0.48) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL11229207 | 0.81 | APEX1 (0.50) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL3864856 | 0.81 | ALDH1A1 (0.50) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL6550416 | 0.80 | TSHR (0.75) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL12388282 | 0.79 | ALDH1A1 (0.45) | ALDH1A1ESRRARARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354512-A1 | POLYMER, COMPOSITION, MOLDED ARTICLE, CURED PRODUCT, AND LAMINATE | JSR CORPORATION (JP) | 2020-11-12 | — | — | US | disclosed |