Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 3/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 2/20 | 0.36 |
| ▸ | GCKR | Q14397 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892107 | 0.81 | PIK3CA (0.52) | EP300PIK3CAMTORTRPC6LRRK2 | |
| SCHEMBL29660767 | 0.81 | PIK3CA (0.52) | EP300PIK3CAMTORTRPC6LRRK2 | |
| SCHEMBL22650409 | 0.81 | MTOR (0.34) | PIK3CAMTORGCKGCKRSMN1; SMN2 | |
| SCHEMBL15651962 | 0.81 | MAPT (0.56) | MAP3K5EEDGAARAD52KDM4E | |
| SCHEMBL30664067 | 0.76 | GAA (0.62) | TRPC6GCKGCKRGAARAD52 | |
| SCHEMBL611882 | 0.76 | GAA (0.62) | TRPC6GCKGCKRGAARAD52 | |
| SCHEMBL22623625 | 0.74 | CHRNA7 (0.53) | EP300EED | |
| SCHEMBL24525802 | 0.73 | GAA (0.40) | PIK3CAMTORGAARAD52KDM4E | |
| SCHEMBL29813620 | 0.73 | GAA (0.40) | PIK3CAMTORGAARAD52KDM4E | |
| SCHEMBL1269255 | 0.73 | PIK3CA (0.43) | PIK3CAMTORTRPC6GCKGCKR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |