Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 7/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.38 |
| ▸ | GCKR | Q14397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892107 | 1.00 | PIK3CA (0.52) | PIK3CAMTOROPRM1OPRL1EP300 | |
| SCHEMBL26944374 | 0.83 | OPRM1 (0.43) | PIK3CAMTOROPRM1OPRL1EP300 | |
| SCHEMBL20037685 | 0.82 | OPRM1 (0.42) | PIK3CAMTOROPRM1OPRL1EP300 | |
| SCHEMBL22650907 | 0.81 | EP300 (0.42) | PIK3CAMTOREP300TRPC6LRRK2 | |
| SCHEMBL20249112 | 0.79 | OPRM1 (0.41) | PIK3CAMTOROPRM1OPRL1EP300 | |
| SCHEMBL5726036 | 0.79 | MAPT (0.56) | PIK3CAMTOROPRM1OPRL1 | |
| SCHEMBL22983954 | 0.77 | MAPT (0.59) | OPRM1OPRL1EP300PIM1AOC3 | |
| SCHEMBL521324 | 0.77 | MAPT (0.58) | PIK3CAMTOR | |
| SCHEMBL29664444 | 0.77 | MAPT (0.58) | PIK3CAMTOR | |
| SCHEMBL1269255 | 0.76 | PIK3CA (0.43) | PIK3CAMTORTRPC6GCKGCKR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502536-A | Heterocyclic compounds as kinase inhibitors | 诺维逊生物股份有限公司 | 2022-05-13 | — | — | CN | disclosed |