Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650907 | 0.81 | EP300 (0.42) | MTORPIK3CADRD3KCNH2GCK | |
| SCHEMBL29813620 | 0.79 | GAA (0.40) | MTORPIK3CADRD3KCNH2METAP2 | |
| SCHEMBL24525802 | 0.79 | GAA (0.40) | MTORPIK3CADRD3KCNH2METAP2 | |
| SCHEMBL13179239 | 0.74 | KMT2A (0.47) | SMN1; SMN2 | |
| SCHEMBL2820372 | 0.74 | SLC6A2 (0.44) | MTORPIK3CANOS3NOS2CHRNB2 | |
| SCHEMBL13179145 | 0.72 | DRD2 (0.45) | DRD3KCNH2SMN1; SMN2DRD2DRD4 | |
| SCHEMBL18291705 | 0.71 | ALDH1A1 (0.40) | MTORPIK3CANOS3NOS2CHRNB2 | |
| SCHEMBL17055336 | 0.71 | HRH3 (0.39) | MTORPIK3CANOS3NOS2CHRNB2 | |
| SCHEMBL19546254 | 0.70 | F2 (0.38) | ELANESMN1; SMN2 | |
| SCHEMBL9834992 | 0.70 | F2 (0.38) | ELANESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |