Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126761 | 0.82 | METAP1 (0.34) | METAP1FDPSTSHR | |
| SCHEMBL20834853 | 0.80 | METAP1 (0.39) | METAP1FDPSTSHR | |
| SCHEMBL20834771 | 0.78 | — | — | |
| SCHEMBL1698634 | 0.77 | METAP1 (0.36) | METAP1FDPSTSHR | |
| SCHEMBL9003255 | 0.77 | METAP1 (0.36) | METAP1FDPSTSHR | |
| SCHEMBL9450759 | 0.75 | METAP1 (0.31) | METAP1 | |
| SCHEMBL20834791 | 0.75 | METAP1 (0.44) | METAP1FDPS | |
| SCHEMBL9003211 | 0.73 | METAP1 (0.31) | METAP1 | |
| SCHEMBL25076405 | 0.72 | — | — | |
| SCHEMBL4610804 | 0.71 | METAP1 (0.34) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227421-A1 | MODIFIED CYCLIC DINUCLEOSIDE COMPOUNDS AS STING MODULATORS | ALIGOS THERAPEUTICS, INC. (US) | 2020-11-12 | — | — | WO | disclosed |