Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.31 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29900210 | 0.83 | SMPD1 (0.48) | FDPSLPAR3LPAR2SMPD1LPAR1 | |
| SCHEMBL1698634 | 0.82 | METAP1 (0.36) | METAP1TSHRFDPSSMPD1 | |
| SCHEMBL9003255 | 0.82 | METAP1 (0.36) | METAP1TSHRFDPSSMPD1 | |
| SCHEMBL22650974 | 0.80 | METAP1 (0.35) | METAP1TSHRFDPS | |
| SCHEMBL20335184 | 0.80 | — | — | |
| SCHEMBL11126761 | 0.79 | METAP1 (0.34) | METAP1TSHRFDPSLPAR3LPAR2 | |
| SCHEMBL20834793 | 0.78 | FDPS (0.37) | METAP1TSHRFDPSLPAR3LPAR2 | |
| SCHEMBL9003211 | 0.78 | METAP1 (0.31) | METAP1 | |
| SCHEMBL4610804 | 0.76 | METAP1 (0.34) | METAP1 | |
| SCHEMBL12038318 | 0.76 | METAP1 (0.30) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019053696-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2019-03-21 | — | — | WO | disclosed |