SCHEMBL9003255

SCHEMBL9003255

CCCC(C)OP(O)(=S)Cl

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 1/20 0.36
FDPS P14324 1/20 0.33
TSHR P16473 1/20 0.31
SMPD1 P17405 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9003211 0.84 METAP1 (0.31) METAP1
SCHEMBL11224371 0.82
SCHEMBL20834853 0.82 METAP1 (0.39) METAP1FDPSTSHRSMPD1
SCHEMBL1698634 0.78 METAP1 (0.36) METAP1FDPSTSHRSMPD1
SCHEMBL22650974 0.77 METAP1 (0.35) METAP1FDPSTSHR
SCHEMBL11126761 0.75 METAP1 (0.34) METAP1FDPSTSHR
SCHEMBL12038318 0.73 METAP1 (0.30) METAP1
SCHEMBL2473811 0.73 SMPD1 (0.50) METAP1FDPSSMPD1
SCHEMBL4610804 0.73 METAP1 (0.34) METAP1
SCHEMBL2471725 0.73 METAP1 (0.48) METAP1FDPSSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0731805-A1 AMIDES OF ACIDS OF PHOSPHORUS FOR THE EXTRACTION OF METALS ZENECA LIMITED (GB) 1996-09-18 EP disclosed
WO-1995015329-A1 AMIDES OF ACIDS OF PHOSPHORUS FOR THE EXTRACTION OF METALS ZENECA LIMITED (GB) 1995-06-08 WO disclosed