SCHEMBL2265203

SCHEMBL2265203

CC1=C(C)C(=O)c2c(C)cccc2C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
USP8 P40818 1/20 0.46
ALDH1A1 P00352 2/20 0.46
NPC1 O15118 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
CASP3 P42574 1/20 0.46
RAB9A P51151 1/20 0.46
HBB P68871 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
DAO P14920 1/20 0.44
CDC25A P30304 1/20 0.43
CDC25B P30305 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6263082 0.91 CA1 (0.47) CA1CA2CA7CA9USP8
SCHEMBL1688847 0.88 ALDH1A1 (0.55) CA1CA2CA7CA9USP8
SCHEMBL12258322 0.86 ALDH1A1 (0.54) CA1CA2CA7CA9USP8
SCHEMBL18059577 0.85 ALDH1A1 (0.46) CA1CA2CA7CA9USP8
SCHEMBL9628339 0.84 CA1 (0.42) CA1CA2CA7CA9USP8
SCHEMBL9628613 0.84 CDC25A (0.62) CA1CA2CA7CA9USP8
SCHEMBL6036681 0.83 TDP2 (0.52) CA1CA2CA7CA9USP8
SCHEMBL29634210 0.83 CA1 (0.52) CA1CA2CA7CA9USP8
SCHEMBL4161497 0.83 CA1 (0.52) CA1CA2CA7CA9USP8
SCHEMBL4019686 0.83 ALDH1A1 (0.55) CA1CA2CA7CA9USP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108715825-B Gene overexpression, strain obtained by gene overexpression and application of gene overexpression 天津大学 2021-03-09 CN disclosed
CN-108715825-A Gene overexpression and the bacterial strain of acquisition, application 天津大学 2018-10-30 CN disclosed
CN-108715824-A Gene overexpression and the bacterial strain of acquisition, application 天津大学 2018-10-30 CN disclosed
CN-105237352-A Process of separating components of a fermentation broth GENOMATICA INC 2016-01-13 CN disclosed
CN-101707877-B Materials and methods for diagnosis and treatment of oxidative stress disorders PRAVDA JAY 2013-01-09 CN disclosed
WO-2012170773-A1 ADJUNCTIVE THERAPY FOR THE TREATMENT OF MITOCHONDRIAL DISORDERS WITH QUINONES AND NAPHTHOQUINONES EDISON PHARMACEUTICALS, INC. (US) 2012-12-13 WO disclosed
CN-101278364-B Electrolytic solution for electrolytic capacitor and electrolytic capacitor MITSUBISHI CHEM CORP 2012-09-05 CN disclosed
CN-102459138-A Method for separating fermentation liquor components GENOMATICA INC 2012-05-16 CN disclosed
US-7998360-B2 Electrolysis solution for electrolytic capacitor, and electrolytic capacitor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-16 US disclosed
CN-101707877-A Materials and methods for diagnosis and treatment of oxidative stress disorders JAY PRAVDA 2010-05-12 CN disclosed
US-20090034160-A1 ELECTROLYSIS SOLUTION FOR ELECTROLYTIC CAPACITOR, AND ELECTROLYTIC CAPACITOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-05 US disclosed
CN-101300356-A Methods and organisms for the growth-coupled production of succinate GENOMATICA INC (US) 2008-11-05 CN disclosed
CN-101278364-A Electrolytic solution for electrolytic capacitor and electrolytic capacitor MITSUBISHI CHEM CORP (JP) 2008-10-01 CN disclosed
EP-1947662-A1 ELECTROLYSIS SOLUTION FOR ELECTROLYTIC CAPACITOR, AND ELECTROLYTIC CAPACITOR Mitsubishi Chemical Corporation (JP) 2008-07-23 EP disclosed
CN-1280419-C Process for producing matter with microbe AJINOMOTO KK (JP) 2006-10-18 CN disclosed
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 WO disclosed
CN-1335401-A Process for producing matter with microbe AJINOMOTO KK (JP) 2002-02-13 CN disclosed