Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353732 | 0.85 | DAO (0.47) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL24195865 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL3295264 | 0.81 | NPSR1 (0.56) | ALDH1A1LMNAHPGDTSHRMAPT | |
| SCHEMBL5351604 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL1798146 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL11631412 | 0.75 | ALDH1A1 (0.57) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL11235459 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL17065257 | 0.75 | GSK3B (0.60) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL3199622 | 0.73 | ALDH1A1 (0.60) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL4058053 | 0.73 | ALDH1A1 (0.60) | ALDH1A1LMNAPRNPRECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227097-A1 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2020-11-12 | — | — | WO | disclosed |