Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | PRNP | P04156 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3186013 | 0.89 | ALDH1A1 (0.66) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL3193059 | 0.87 | ALDH1A1 (0.69) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL3176363 | 0.85 | LMNA (0.71) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL262537 | 0.84 | DAO (0.50) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL4058053 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL1798146 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL10639931 | 0.82 | ALDH1A1 (0.63) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL2690014 | 0.82 | F2 (0.48) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL5887893 | 0.79 | HPGD (0.53) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL10636804 | 0.79 | LMNA (0.55) | ALDH1A1LMNAPRNPRECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080389-A | Nrf2 activating compound | 千寿制药株式会社 | 2022-02-22 | — | — | CN | disclosed |
| US-7659411-B2 | Process for producing 2-acylthiophene compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2010-02-09 | — | — | US | disclosed |
| CN-100455578-C | Process for producing 2-acylthiophene compound | SUMITOMO SEIKA CHEMICALS (JP) | 2009-01-28 | — | — | CN | disclosed |
| US-20070149787-A1 | Process for producing 2-acylthiophene compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| CN-1886396-A | Process for producing 2-acylthiophene compound | SUMITOMO SEIKA CHEMICALS (JP) | 2006-12-27 | — | — | CN | disclosed |
| EP-1695972-A1 | PROCESS FOR PRODUCING 2-ACYLTHIOPHENE COMPOUND | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149787-A1 | Process for producing 2-acylthiophene compound | AGPAT2, MOGAT2, TPST2 | ALDH1A1 111/4885LMNA 4557/4885PRNP 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.