SCHEMBL22653085

SCHEMBL22653085

Nc1c2ccccc2c(N)c2c1ccc1ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.50
HSD17B10 Q99714 8/20 0.48
ALDH1A1 P00352 7/20 0.48
TSHR P16473 4/20 0.48
TDP1 Q9NUW8 3/20 0.48
CYP2A6 P11509 1/20 0.48
HPGD P15428 6/20 0.47
CASP1 P29466 3/20 0.47
CASP7 P55210 3/20 0.47
RAB9A P51151 3/20 0.47
HIF1A Q16665 3/20 0.47
CYP3A4 P08684 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 2/20 0.47
MAPK1 P28482 1/20 0.47
KEAP1 Q14145 1/20 0.44
KDM4E B2RXH2 3/20 0.43
GLA P06280 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAOA P21397 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28686407 0.86 HPRT1 (0.55) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL22142550 0.84 HPRT1 (0.54) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL4916286 0.78 HSD17B10 (0.60) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL21557097 0.77 HPRT1 (0.50) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL20053356 0.76 ALDH1A1 (0.62) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL18600599 0.75 HSD17B10 (0.50) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL3341788 0.75 HPRT1 (0.67) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL29517920 0.75 HPRT1 (0.67) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL4847084 0.75 HPRT1 (0.67) HPRT1HSD17B10ALDH1A1TSHRTDP1
SCHEMBL29401594 0.74 ALDH1A1 (0.58) HSD17B10ALDH1A1TSHRTDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020225778-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2020-11-12 WO disclosed