Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22633364 | 1.00 | KDM4C (0.41) | KDM4CMEN1KMT2APOLBPLA2G10 | |
| SCHEMBL3506600 | 0.98 | KDM4C (0.42) | KDM4CMEN1KMT2APOLBPLA2G10 | |
| SCHEMBL4824612 | 0.92 | MEN1 (0.48) | KDM4CMEN1KMT2APOLBPLA2G10 | |
| SCHEMBL24209614 | 0.90 | MEN1 (0.47) | KDM4CMEN1KMT2APLA2G10PLA2G2A | |
| SCHEMBL27129003 | 0.86 | KDM4C (0.41) | KDM4CMEN1KMT2APOLBCA1 | |
| SCHEMBL27032269 | 0.86 | KDM4C (0.41) | KDM4CMEN1KMT2APOLBCA1 | |
| SCHEMBL27031868 | 0.86 | KDM4C (0.41) | KDM4CMEN1KMT2APOLBCA1 | |
| SCHEMBL19750677 | 0.86 | KDM4C (0.37) | KDM4CMEN1KMT2APOLBCA1 | |
| SCHEMBL27031980 | 0.85 | KDM4C (0.47) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL21068487 | 0.85 | KDM4C (0.41) | KDM4CMEN1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11576986-B2 | Macrocyclic chelators and methods of use thereof | JANSSEN BIOTECH, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| EP-3966211-A1 | MACROCYCLIC CHELATORS AND METHODS OF USE THEREOF | Janssen Biotech, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |
| WO-2020229974-A1 | MACROCYCLIC CHELATORS AND METHODS OF USE THEREOF | JANSSEN BIOTECH, INC. (US) | 2020-11-19 | — | — | WO | disclosed |
| US-20200353105-A1 | Macrocyclic Chelators and Methods of Use Thereof | JANSSEN BIOTECH, INC. | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200353105-A1 | Macrocyclic Chelators and Methods of Use Thereof | CLASP1, CLTC, CD47 | KDM4C 1287/4885MEN1 173/4885KMT2A 2417/4885 |
| US-11576986-B2 | Macrocyclic chelators and methods of use thereof | CLASP1, CLTC, CD47 | KDM4C 1287/4885MEN1 173/4885KMT2A 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.