SCHEMBL4824612

SCHEMBL4824612

c1ccc(COCC(COCCCCCCOC2CCCCO2)OCCCCCCOC2CCCCO2)cc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
PLA2G2A P14555 3/20 0.40
PLA2G10 O15496 2/20 0.40
KDM4C Q9H3R0 1/20 0.40
TLR2 O60603 4/20 0.35
PLA2G1B P04054 1/20 0.35
PLA2G5 P39877 1/20 0.35
POLB P06746 1/20 0.34
CA1 P00915 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24209614 0.96 MEN1 (0.47) MEN1KMT2APLA2G2APLA2G10KDM4C
SCHEMBL22633364 0.92 KDM4C (0.41) MEN1KMT2APLA2G2APLA2G10KDM4C
SCHEMBL22653145 0.92 KDM4C (0.41) MEN1KMT2APLA2G2APLA2G10KDM4C
SCHEMBL3506600 0.92 KDM4C (0.42) MEN1KMT2APLA2G2APLA2G10KDM4C
SCHEMBL6558221 0.85 MEN1 (0.48) MEN1KMT2AKDM4CTLR2L3MBTL1
SCHEMBL19750677 0.85 KDM4C (0.37) MEN1KMT2AKDM4CPOLBCA1
SCHEMBL9359454 0.84 MEN1 (0.39) MEN1KMT2APLA2G2APLA2G10KDM4C
SCHEMBL9359448 0.84 MEN1 (0.39) MEN1KMT2APLA2G2APLA2G10KDM4C
SCHEMBL21068591 0.84 MEN1 (0.52) MEN1KMT2AKDM4CL3MBTL1TDP1
SCHEMBL22787023 0.84 MEN1 (0.52) MEN1KMT2AKDM4CL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293447-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF SANOFI PASTEUR (FR) 2023-09-21 US disclosed
US-20230293447-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF SANOFI PASTEUR (FR) 2023-09-21 US disclosed
CN-116194084-A Cleavable lipid compounds, compositions containing the same and uses thereof 赛诺菲巴斯德有限公司 2023-05-30 CN disclosed
EP-4182296-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF Sanofi Pasteur (FR) 2023-05-24 EP disclosed
WO-2022013439-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF SANOFI PASTEUR (FR) 2022-01-20 WO disclosed
US-7321059-B2 Compounds for use as surfactants GLAXO GROUP LIMITED (GB) 2008-01-22 US disclosed
EP-1436007-B1 COMPOUNDS FOR USE AS SURFACTANTS GLAXO GROUP LTD (GB) 2005-03-30 EP disclosed
US-20050048024-A1 Compounds for use as surfactants GLAXO GROUP LIMITED (GB) 2005-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293447-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF MTTP, CETP, LNPEP MEN1 3390/4885KMT2A 645/4885PLA2G2A 688/4885
US-20050048024-A1 Compounds for use as surfactants SGMS1, AQP1, F12 MEN1 113/4885KMT2A 4089/4885PLA2G2A 2319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.