Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206985 | 0.76 | — | — | |
| SCHEMBL22657774 | 0.76 | — | — | |
| SCHEMBL22657863 | 0.75 | — | — | |
| SCHEMBL22657994 | 0.72 | — | — | |
| SCHEMBL22657819 | 0.71 | — | — | |
| SCHEMBL771963 | 0.70 | — | — | |
| SCHEMBL22657793 | 0.69 | MAPK1 (0.32) | KMT2A | |
| SCHEMBL5025313 | 0.69 | — | — | |
| SCHEMBL3954336 | 0.68 | ALDH1A1 (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18228341 | 0.68 | SMN1; SMN2 (0.32) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228637-A1 | SUBSTITUTED 1-AMINO-1H-IMIDAZOLE-5-CARBOXAMIDE AS BRUTON'S TYROSINE KINASE INHIBITORS | HENAN NORMAL UNIVERSITY (CN) | 2020-11-19 | — | — | WO | disclosed |