⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18228341 | 0.98 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL1206985 | 0.93 | — | — | |
| SCHEMBL2644912 | 0.80 | L3MBTL1 (0.38) | — | |
| SCHEMBL1208896 | 0.79 | — | — | |
| SCHEMBL22657847 | 0.79 | — | — | |
| SCHEMBL5202206 | 0.78 | — | — | |
| SCHEMBL2947547 | 0.76 | MEN1 (0.33) | — | |
| SCHEMBL7246530 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL361276 | 0.76 | PKM (0.33) | — | |
| SCHEMBL7244913 | 0.76 | RIPK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000871-A1 | GEM-DISUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IDH INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-01-05 | — | — | US | claimed |
| CN-115038700-A | Gem disubstituted heterocyclic compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2022-09-09 | — | — | CN | claimed |
| CN-114040912-A | Compounds for the treatment of kinase-dependent disorders | 埃克塞里艾克西斯公司 | 2022-02-11 | — | — | CN | claimed |
| EP-3917508-A1 | MITOFUSIN ACTIVATORS AND METHODS OF USE THEREOF | Mitochondria Emotion, Inc. (US) | 2021-12-08 | — | — | EP | claimed |
| US-20210046028-A1 | MITOFUSIN ACTIVATORS AND METHODS OF USE THEREOF | MITOCHONDRIA EMOTION, INC. (US) | 2021-02-18 | — | — | US | claimed |
| EP-3057950-B1 | PHENYL LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-02 | — | — | EP | claimed |
| US-10829466-B2 | Stilbene derivative and preparation method thereof | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-11-10 | — | — | US | claimed |
| US-20200345669-A1 | MITOFUSIN ACTIVATORS AND METHODS OF USE THEREOF | MITOCHONDRIA EMOTION, INC. (US) | 2020-11-05 | — | — | US | claimed |
| WO-2020159576-A1 | MITOFUSIN ACTIVATORS AND METHODS OF USE THEREOF | MITOCHONDRIA EMOTION, INC. (US) | 2020-08-06 | — | — | WO | claimed |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-05-14 | — | — | US | claimed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | claimed |
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | claimed |
| WO-2009016460-A2 | PYRAZOLE COMPOUNDS AND THEIR USE AS RAF INHIBITORS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | claimed |
| US-20080176843-A1 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2008-07-24 | — | — | US | claimed |
| US-20080146536-A1 | 2-Aminoimidazopyridines for treating neurodegenerative diseases | PHARMACOPEIA, INC. (US) | 2008-06-19 | — | — | US | claimed |
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | claimed |
| WO-2008021375-A2 | MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-02-21 | — | — | WO | claimed |
| WO-2008020024-A1 | NTETRAHYDROPYRIDOTHIOPHENE DERIVATIVES FOR THE TREATMENT OF CANCER | 4SC AG (DE) | 2008-02-21 | — | — | WO | claimed |
| WO-2007022305-A2 | 2-AMINOIMIDAZOPYRIDINES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-02-22 | — | — | WO | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |