Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056992 | 0.82 | HTR1A (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Akuammigine SCHEMBL17088325 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Akuammigine SCHEMBL15384550 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Akuammigine SCHEMBL15384548 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Akuammigine SCHEMBL15384556 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Tetrahydroalstonine SCHEMBL564502 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Akuammigine SCHEMBL17088324 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Akuammigine SCHEMBL15384543 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Akuammigine SCHEMBL15384547 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 | |
| Akuammigine SCHEMBL309915 | 0.79 | CYP2D6 (1.00) | HTR1AMEN1KMT2ACYP2D6CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220228180-A1 | Methods for production of strictosidine aglycone and monoterpenoid indole alkaloids | DANMARKS TEKNISKE UNIVERSITET (DK) | 2022-07-21 | — | — | US | disclosed |
| EP-3969603-A1 | METHODS FOR PRODUCTION OF STRICTOSIDINE AGLYCONE AND MONOTERPENOID INDOLE ALKALOIDS | Danmarks Tekniske Universitet (DK) | 2022-03-23 | — | — | EP | disclosed |
| WO-2020229516-A1 | METHODS FOR PRODUCTION OF STRICTOSIDINE AGLYCONE AND MONOTERPENOID INDOLE ALKALOIDS | DANMARKS TEKNISKE UNIVERSITET (DK) | 2020-11-19 | — | — | WO | disclosed |