SCHEMBL22658673

SCHEMBL22658673

O=C(O)/C=C\C(=O)Nc1ccc2oc(NC(=O)/C=C\C(=O)O)nc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.58
▸ KDM4E B2RXH2 6/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ MAPT P10636 5/20 0.57
▸ SMN1; SMN2 Q16637 4/20 0.57
▸ LPAR2 Q9HBW0 2/20 0.51
▸ LPAR1 Q92633 1/20 0.51
▸ LPAR3 Q9UBY5 1/20 0.49
▸ L3MBTL1 Q9Y468 3/20 0.48
▸ THRB P10828 2/20 0.48
▸ GAA P10253 2/20 0.48
▸ TDP2 O95551 1/20 0.48
▸ POLB P06746 3/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ NMT1 P30419 1/20 0.47
▸ PKM P14618 2/20 0.46
▸ IL6 P05231 1/20 0.46
▸ STAT3 P40763 1/20 0.46
▸ NPC1 O15118 3/20 0.45
▸ RAB9A P51151 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22664035 0.93 ALDH1A1 (0.54) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL22663680 0.83 ALDH1A1 (0.60) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL22664020 0.78 PPARG (0.54) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL22658725 0.73 NPC1 (0.67) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL11137034 0.72 LPAR2 (0.88) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL11133691 0.72 LPAR2 (0.88) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL3620965 0.71 MAPT (0.66) KMT2AMAPTSMN1; SMN2THRBGAA
SCHEMBL3620968 0.71 MAPT (0.66) KMT2AMAPTSMN1; SMN2THRBGAA
SCHEMBL2248018 0.70 HPSE (0.74) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2
SCHEMBL441804 0.69 LPAR2 (1.00) ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020232338-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 — — WO claimed
US-11061328-B2 Positive tone photosensitive compositions containing amic acid as latent base catalyst PROMERUS, LLC (US) 2021-07-13 — — US disclosed
WO-2020232338-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 — — WO disclosed
WO-2020232338-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 — — WO disclosed
US-20200363722-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 — — US disclosed
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