SCHEMBL22658792

SCHEMBL22658792

O=C(O)/C=C\C(=O)Nc1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4ccc(NC(=O)/C=C\C(=O)O)cc4)cc3)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.79
MAPT P10636 4/20 0.79
POLB P06746 2/20 0.79
L3MBTL1 Q9Y468 2/20 0.79
SMN1; SMN2 Q16637 1/20 0.79
LPAR2 Q9HBW0 2/20 0.68
LPAR3 Q9UBY5 2/20 0.68
LPAR1 Q92633 1/20 0.68
THRB P10828 3/20 0.59
KMT2A Q03164 2/20 0.57
TDP2 O95551 1/20 0.55
GAA P10253 1/20 0.55
NMT1 P30419 1/20 0.54
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.52
LMNA P02545 1/20 0.51
MEN1 O00255 1/20 0.50
TGM2 P21980 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22663672 0.91 ALDH1A1 (0.68) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL15078372 0.91 ALDH1A1 (0.68) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL15078384 0.87 LPAR1 (0.70) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL16168889 0.87 LPAR1 (0.70) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL22664016 0.86 ALDH1A1 (0.59) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL4740156 0.84 ALDH1A1 (1.00) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL4740155 0.84 ALDH1A1 (1.00) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL15631749 0.84 ALDH1A1 (0.60) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL23966420 0.82 ALDH1A1 (0.84) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2
SCHEMBL12650708 0.82 ALDH1A1 (0.84) ALDH1A1MAPTPOLBL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020232338-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 WO claimed
US-11061328-B2 Positive tone photosensitive compositions containing amic acid as latent base catalyst PROMERUS, LLC (US) 2021-07-13 US disclosed
WO-2020232338-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 WO disclosed
US-20200363722-A1 POSITIVE TONE PHOTOSENSITIVE COMPOSITIONS CONTAINING AMIC ACID AS LATENT BASE CATALYST PROMERUS, LLC (US) 2020-11-19 US disclosed