Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.90 |
| ▸ | POLB | P06746 | 1/20 | 0.90 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.85 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.85 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.85 |
| ▸ | TGM2 | P21980 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740155 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL18514204 | 0.92 | LPAR2 (1.00) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL23966420 | 0.87 | ALDH1A1 (0.84) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL12650708 | 0.87 | ALDH1A1 (0.84) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL21758069 | 0.85 | MTNR1A (0.74) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL22664021 | 0.85 | LPAR2 (0.85) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL22658792 | 0.84 | ALDH1A1 (0.79) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL1169889 | 0.84 | ALDH1A1 (0.79) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL2831352 | 0.84 | ALDH1A1 (0.79) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL1683255 | 0.84 | ALDH1A1 (0.79) | ALDH1A1MAPTSMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092681-A1 | GHRELIN RECEPTOR MODULATORS | PROSIDION LIMITED (GB) | 2008-08-07 | — | — | WO | disclosed |