Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1536105 | 0.88 | YTHDC1 (0.46) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL4351032 | 0.88 | YTHDC1 (0.46) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL1543222 | 0.87 | G6PC1 (0.48) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL1543217 | 0.87 | G6PC1 (0.48) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL1543221 | 0.87 | G6PC1 (0.48) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL1543349 | 0.84 | YTHDC1 (0.51) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL1543347 | 0.84 | YTHDC1 (0.51) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL21595464 | 0.77 | YTHDC1 (0.44) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL21595465 | 0.77 | YTHDC1 (0.44) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 | |
| SCHEMBL12055458 | 0.77 | YTHDC1 (0.36) | YTHDC1SLC6A2SLC6A4SLC6A3G6PC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220242886-A1 | CHEMICAL COMPOUNDS | CANAAN XII L.P. | 2022-08-04 | — | — | US | disclosed |
| US-20220242886-A1 | CHEMICAL COMPOUNDS | CANAAN XII L.P. | 2022-08-04 | — | — | US | disclosed |
| US-11306108-B2 | Chemical compounds | BORAH, INC. (US) | 2022-04-19 | — | — | US | disclosed |
| EP-3969458-A1 | CHEMICAL COMPOUNDS | Boragen, Inc. (US) | 2022-03-23 | — | — | EP | disclosed |
| US-20210188879-A1 | CHEMICAL COMPOUNDS | CANAAN XII L.P. | 2021-06-24 | — | — | US | disclosed |
| US-20210188879-A1 | CHEMICAL COMPOUNDS | CANAAN XII L.P. | 2021-06-24 | — | — | US | disclosed |
| WO-2020232470-A1 | CHEMICAL COMPOUNDS | Boragen, Inc. (US) | 2020-11-19 | — | — | WO | disclosed |
| WO-2020232470-A1 | CHEMICAL COMPOUNDS | Boragen, Inc. (US) | 2020-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188879-A1 | CHEMICAL COMPOUNDS | JAK2, JAK1, JAK3 | YTHDC1 4458/4885SLC6A2 4712/4885SLC6A4 4433/4885 |
| US-20220242886-A1 | CHEMICAL COMPOUNDS | JAK2, JAK1, JAK3 | YTHDC1 4458/4885SLC6A2 4712/4885SLC6A4 4433/4885 |
| US-11306108-B2 | Chemical compounds | JAK2, JAK1, JAK3 | YTHDC1 4458/4885SLC6A2 4712/4885SLC6A4 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.