Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.42 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660077 | 0.86 | GSK3B (0.48) | — | |
| SCHEMBL29533531 | 0.86 | GSK3B (0.48) | — | |
| SCHEMBL29676504 | 0.85 | AAK1 (0.48) | AAK1BTKROCK2MKNK2HDAC1 | |
| SCHEMBL16794005 | 0.85 | AAK1 (0.48) | AAK1BTKROCK2MKNK2HDAC1 | |
| SCHEMBL22659490 | 0.84 | ABL1 (0.42) | AAK1GAKROCK2CHRNA1SLC6A2 | |
| SCHEMBL22659499 | 0.84 | ABL1 (0.42) | AAK1GAKROCK2CHRNA1SLC6A2 | |
| SCHEMBL29532924 | 0.84 | ABL1 (0.42) | AAK1GAKROCK2CHRNA1SLC6A2 | |
| SCHEMBL29533400 | 0.84 | ABL1 (0.42) | AAK1GAKROCK2CHRNA1SLC6A2 | |
| SCHEMBL22664858 | 0.82 | ABL1 (0.44) | — | |
| SCHEMBL22664861 | 0.82 | ABL1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232330-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC. (US) | 2020-11-19 | — | — | WO | disclosed |