Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659490 | 1.00 | ABL1 (0.42) | ABL1TYK2AAK1MAP4K1GSK3B | |
| SCHEMBL22659499 | 1.00 | ABL1 (0.42) | ABL1TYK2AAK1MAP4K1GSK3B | |
| SCHEMBL29532924 | 1.00 | ABL1 (0.42) | ABL1TYK2AAK1MAP4K1GSK3B | |
| SCHEMBL22664861 | 0.93 | ABL1 (0.44) | ABL1MAP4K1 | |
| SCHEMBL29533532 | 0.93 | ABL1 (0.44) | ABL1MAP4K1 | |
| SCHEMBL22664858 | 0.93 | ABL1 (0.44) | ABL1MAP4K1 | |
| SCHEMBL29533531 | 0.91 | GSK3B (0.48) | ABL1GSK3BMAPK14 | |
| SCHEMBL22660077 | 0.91 | GSK3B (0.48) | ABL1GSK3BMAPK14 | |
| SCHEMBL22659458 | 0.88 | TYK2 (0.47) | ABL1TYK2MAP4K1GSK3BBUB1 | |
| SCHEMBL22664870 | 0.84 | AAK1 (0.42) | AAK1WNT3AGAKROCK2CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969124-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2022-03-23 | — | — | EP | disclosed |