Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 16/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660077 | 1.00 | GSK3B (0.48) | GSK3BMAPK14PIK3C3MAPK8MAPK10 | |
| SCHEMBL22659499 | 0.91 | ABL1 (0.42) | GSK3BMAPK14ABL1 | |
| SCHEMBL29533400 | 0.91 | ABL1 (0.42) | GSK3BMAPK14ABL1 | |
| SCHEMBL29532924 | 0.91 | ABL1 (0.42) | GSK3BMAPK14ABL1 | |
| SCHEMBL22659490 | 0.91 | ABL1 (0.42) | GSK3BMAPK14ABL1 | |
| SCHEMBL22664858 | 0.90 | ABL1 (0.44) | ABL1 | |
| SCHEMBL29533532 | 0.90 | ABL1 (0.44) | ABL1 | |
| SCHEMBL22664861 | 0.90 | ABL1 (0.44) | ABL1 | |
| SCHEMBL22664601 | 0.89 | GSK3B (0.47) | GSK3BPIK3C3MAPK8MAPK10 | |
| SCHEMBL29533456 | 0.89 | GSK3B (0.47) | GSK3BPIK3C3MAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969124-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2022-03-23 | — | — | EP | disclosed |