SCHEMBL2266497

SCHEMBL2266497

N[C@H](C(=O)O)C(F)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.48
SLC1A3 P43003 12/20 0.40
SLC1A2 P43004 12/20 0.40
SLC1A1 P43005 11/20 0.40
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
PTGS1 P23219 1/20 0.33
SLC7A11 Q9UPY5 1/20 0.33
GRM2 Q14416 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5298388 1.00 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL865283 0.82 SLC7A5 (0.43) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL9183338 0.82 SLC7A5 (0.43) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL865284 0.82 SLC7A5 (0.43) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL757841 0.78
SCHEMBL3798816 0.78
SCHEMBL1007447 0.75 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL29957453 0.75 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL468084 0.75 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2
SCHEMBL600021 0.75 SLC7A5 (0.62) SLC7A5SLC1A3SLC1A2SLC1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240325517-A1 COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE INIMMUNE CORPORATION 2024-10-03 US disclosed
CN-117623959-A Synthesis method of threo-3-fluoro-N-9-phenyl-9-fluorene-L-tert-butyl aspartate 吉尔多肽生物制药(大连市)有限公司 2024-03-01 CN disclosed
EP-4213943-A1 COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE The University Of Montana (US) 2023-07-26 EP disclosed
WO-2022060905-A1 COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE THE UNIVERSITY OF MONTANA (US) 2022-03-24 WO disclosed
US-8445440-B2 Dimeric IAP inhibitors NOVARTIS AG (CH) 2013-05-21 US disclosed
EP-2539333-A1 DIMERIC IAP INHIBITORS Novartis AG (CH) 2013-01-02 EP disclosed
WO-2011104266-A1 DIMERIC IAP INHIBITORS NOVARTIS AG (CH) 2011-09-01 WO disclosed
US-20110206690-A1 DIMERIC IAP INHIBITORS NOVARTIS AG (CH) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240325517-A1 COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE TLR8, TLR3, TLR4 SLC7A5 3298/4885SLC1A3 4056/4885SLC1A2 4497/4885
US-20110206690-A1 DIMERIC IAP INHIBITORS XIAP, BIRC5, BIRC2 SLC7A5 3081/4885SLC1A3 4126/4885SLC1A2 4283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.