Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 9/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22009135 | 0.91 | POLB (0.41) | DUTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL22110702 | 0.91 | POLB (0.41) | DUTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL20879386 | 0.90 | DUT (0.51) | DUT | |
| SCHEMBL23394128 | 0.87 | POLB (0.39) | DUTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL22666153 | 0.86 | DUT (0.48) | DUT | |
| SCHEMBL20879441 | 0.85 | POLB (0.39) | DUTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL20879436 | 0.84 | DUT (0.48) | DUT | |
| SCHEMBL22666040 | 0.84 | POLB (0.37) | DUTPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL25567944 | 0.82 | DUT (0.46) | DUT | |
| SCHEMBL22241508 | 0.80 | DUT (0.43) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3738969-A1 | 2'-CHLORO AMINOPYRIMIDINONE AND PYRIMIDINE DIONE NUCLEOSIDES FOR USE IN TREATING PNEUMOVIRINAE VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |