Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 10/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20879386 | 0.91 | DUT (0.51) | DUTP2RY6TOP2A | |
| SCHEMBL22666153 | 0.87 | DUT (0.48) | DUTP2RY6TOP2A | |
| SCHEMBL20879436 | 0.87 | DUT (0.48) | DUTP2RY6TOP2A | |
| SCHEMBL22110552 | 0.85 | DUT (0.47) | DUTP2RY6TOP2A | |
| SCHEMBL22241508 | 0.83 | DUT (0.43) | DUTP2RY6TOP2A | |
| SCHEMBL22666158 | 0.82 | DUT (0.43) | DUT | |
| SCHEMBL24928459 | 0.81 | DUT (0.49) | DUTP2RY6TOP2A | |
| SCHEMBL26277416 | 0.79 | DUT (0.43) | DUTP2RY6TOP2A | |
| SCHEMBL25401927 | 0.79 | DUT (0.43) | DUTP2RY6TOP2A | |
| SCHEMBL21152287 | 0.79 | DUT (0.45) | DUTP2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013340-B9 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN PHARMACEUTICALS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3013340-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |