Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946795 | 0.88 | TK1 (0.49) | TK1CYP2C19CYP1A2GAAMEN1 | |
| SCHEMBL22020875 | 0.88 | MAPK1 (0.41) | TK1ALDH1A1MAPK1TK2HPGD | |
| SCHEMBL25799801 | 0.87 | TK1 (0.48) | TK1CYP2C19CYP1A2GAAMEN1 | |
| SCHEMBL22946803 | 0.87 | TK1 (0.47) | TK1CYP2C19CYP1A2GAAMEN1 | |
| SCHEMBL22020961 | 0.86 | TK1 (0.47) | TK1CYP2C19CYP1A2GAAMEN1 | |
| SCHEMBL22380811 | 0.86 | TK1 (0.47) | TK1CYP2C19CYP1A2GAAMEN1 | |
| SCHEMBL22260568 | 0.79 | TK1 (0.43) | TK1CYP2C19CYP1A2GAAMAPK1 | |
| SCHEMBL26793575 | 0.78 | MAPK1 (0.41) | TK1ALDH1A1MAPK1TK2HPGD | |
| SCHEMBL22198654 | 0.76 | TK1 (0.39) | TK1ALDH1A1MAPK1TK2HPGD | |
| SCHEMBL21090689 | 0.76 | TK1 (0.39) | TK1ALDH1A1MAPK1TK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200362337-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-11-19 | — | — | US | disclosed |