Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22666659 | 0.91 | TSHR (0.58) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 | |
| SCHEMBL20534355 | 0.91 | TSHR (0.58) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 | |
| SCHEMBL25613492 | 0.91 | TSHR (0.58) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 | |
| SCHEMBL25613459 | 0.91 | TSHR (0.58) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 | |
| Benzenethiol SCHEMBL27899498 | 0.84 | TSHR (0.58) | TSHRSMN1; SMN2POLBCYP2D6CA12 | |
| SCHEMBL26705907 | 0.83 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 | |
| SCHEMBL25613451 | 0.83 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 | |
| SCHEMBL26673690 | 0.83 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 | |
| SCHEMBL25613528 | 0.83 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 | |
| SCHEMBL25613491 | 0.83 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2POLBCYP2D6PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802187-B2 | Polyphenylenes, methods, and uses thereof | SIMON FRASER UNIVERSITY (CA) | 2023-10-31 | — | — | US | disclosed |
| US-20200362129-A1 | POLYPHENYLENES, METHODS, AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200362129-A1 | POLYPHENYLENES, METHODS, AND USES THEREOF | PICALM, PARN, PHOSPHO1 | TSHR 4449/4885SMN1; SMN2 3835/4885POLB 2273/4885 |
| US-11802187-B2 | Polyphenylenes, methods, and uses thereof | PICALM, PARN, PHOSPHO1 | TSHR 4449/4885SMN1; SMN2 3835/4885POLB 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.