Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26673690 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRCYP2D6MAPK1LMNA | |
| SCHEMBL25613528 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRCYP2D6MAPK1LMNA | |
| SCHEMBL25613491 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRCYP2D6MAPK1LMNA | |
| SCHEMBL25613451 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRCYP2D6MAPK1LMNA | |
| SCHEMBL25613459 | 0.91 | TSHR (0.58) | SMN1; SMN2TSHRCYP2D6LMNAALDH1A1 | |
| SCHEMBL25613492 | 0.91 | TSHR (0.58) | SMN1; SMN2TSHRCYP2D6LMNAALDH1A1 | |
| SCHEMBL20534355 | 0.91 | TSHR (0.58) | SMN1; SMN2TSHRCYP2D6LMNAALDH1A1 | |
| SCHEMBL22666659 | 0.91 | TSHR (0.58) | SMN1; SMN2TSHRCYP2D6LMNAALDH1A1 | |
| SCHEMBL25613447 | 0.87 | ALDH1A1 (0.42) | SMN1; SMN2TSHRCYP2D6MAPK1LMNA | |
| SCHEMBL25613449 | 0.87 | ALDH1A1 (0.42) | SMN1; SMN2TSHRCYP2D6MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348659-A1 | BRANCHED AND HYPERBRANCHED IONOMERIC POLYMERS AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2023-11-02 | — | — | US | disclosed |