Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 11/20 | 1.00 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.65 |
| ▸ | CDK9 | P50750 | 5/20 | 0.65 |
| ▸ | PARP1 | P09874 | 3/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.59 |
| ▸ | CDK2 | P24941 | 3/20 | 0.59 |
| ▸ | GABRP | O00591 | 1/20 | 0.59 |
| ▸ | GABRD | O14764 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.59 |
| ▸ | CCNC | P24863 | 1/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22667248 | 0.89 | USP8 (1.00) | USP8CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL28953790 | 0.87 | USP8 (1.00) | USP8CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL22667264 | 0.84 | USP8 (1.00) | USP8CCNT1CDK9PARP1PARP2 | |
| SCHEMBL22667252 | 0.84 | USP8 (0.92) | USP8CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL22667238 | 0.78 | CCNT1 (1.00) | USP8CCNT1CDK9PARP1PARP2 | |
| 4'-Hydroxywogonin SCHEMBL29455103 | 0.78 | GABRP (0.81) | USP8CCNT1CDK9CCNA2CDK2 | |
| 4'-Hydroxywogonin SCHEMBL738981 | 0.78 | GABRP (0.81) | USP8CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL22667243 | 0.77 | USP8 (0.77) | USP8CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL22667251 | 0.77 | USP8 (0.81) | USP8CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL22667241 | 0.76 | CCNT1 (0.82) | USP8CCNT1CDK9CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228513-A1 | NOVEL CDK9 INHIBITOR BASED ON BENZOPYRAN STRUCTURE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2020-11-19 | — | — | WO | disclosed |