4'-Hydroxywogonin

4'-Hydroxywogonin

SCHEMBL738981

COc1c(O)cc(O)c2c(=O)cc(-c3ccc(O)cc3)oc12

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.81
GABRD O14764 2/20 0.81
GABRA1 P14867 2/20 0.81
GABRB1 P18505 2/20 0.81
GABRG2 P18507 2/20 0.81
GABRB3 P28472 2/20 0.81
GABRA5 P31644 2/20 0.81
GABRA3 P34903 2/20 0.81
GABRA2 P47869 2/20 0.81
GABRB2 P47870 2/20 0.81
GABRA4 P48169 2/20 0.81
GABRE P78334 2/20 0.81
GABRA6 Q16445 2/20 0.81
GABRG1 Q8N1C3 2/20 0.81
GABRG3 Q99928 2/20 0.81
GABRQ Q9UN88 2/20 0.81
KDM1A O60341 1/20 0.81
CCNT1 O60563 1/20 0.81
PKM P14618 1/20 0.81
CCNA2 P20248 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4'-Hydroxywogonin SCHEMBL29455103 1.00 GABRP (0.81) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL6359647 0.90 ACHE (0.81) GABRPGABRDGABRA1GABRB1GABRG2
Wogonin SCHEMBL139083 0.89 GABRP (1.00) GABRPGABRDGABRA1GABRB1GABRG2
Wogonin SCHEMBL29632729 0.89 GABRP (1.00) GABRPGABRDGABRA1GABRB1GABRG2
Wogonin SCHEMBL29030574 0.88 GABRP (0.97) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29435849 0.88 BCL2 (1.00) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26114003 0.88 BCL2 (1.00) GABRPGABRDGABRA1GABRB1GABRG2
Wogonin SCHEMBL28516605 0.88 GABRP (0.97) GABRPGABRDGABRA1GABRB1GABRG2
Wogonin SCHEMBL29025251 0.88 GABRP (0.97) GABRPGABRDGABRA1GABRB1GABRG2
Wogonin SCHEMBL27921406 0.88 GABRP (0.97) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130197015-A1 NOVEL METHOD TO IMPROVE THE SAFETY AND EFFICACY OF CAFFEINE Pondera Biotechnologies, LLC (US) 2013-08-01 US claimed
US-20130156874-A1 METHODS AND COMPOSITIONS FOR TREATING DISTRESS DYSFUNCTION AND ENHANCING SAFETY AND EFFICACY OF SPECIFIC MEDICATIONS Pondera Biotechnologies, LLC (US) 2013-06-20 US claimed
US-20120237570-A1 METHODS AND COMPOSITIONS FOR TREATING DISTRESS DYSFUNCTION AND ENHANCING SAFETY AND EFFICACY OF SPECIFIC MEDICATIONS Pondera Biotechnologies, LLC 2012-09-20 US claimed
WO-2011087755-A2 METHODS AND COMPOSITIONS FOR TREATING DISTRESS DYSFUNCTION AND ENHANCING SAFETY AND EFFICACY OF SPECIFIC MEDICATIONS Pondera Biotechnologies, LLC (US) 2011-07-21 WO claimed
US-20110159048-A1 METHODS AND COMPOSITIONS FOR TREATING DISTRESS DYSFUNCTION AND ENHANCING SAFETY AND EFFICACY OF SPECIFIC MEDICATIONS Pondera Biotechnologies, LLC 2011-06-30 US claimed
EP-0332478-B1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECH (FR) 1992-03-25 EP claimed
WO-1989008447-A1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECHERCHE (FR) 1989-09-21 WO claimed
EP-0332478-A1 Liposomes containing Scutellaria extracts LVMH RECHERCHE (FR) 1989-09-13 EP claimed
JP-9227373-A None JP disclosed
CN-115078581-B UHPLC-Q-TOF/MS based method for identifying bupleurum, cassia twig and dried ginger decoction-free ingredients 上海长征医院 2024-08-27 CN disclosed
CN-115078581-A Method for identifying components of radix bupleuri, cassia twig and dried ginger decoction-free preparation based on UHPLC-Q-TOF/MS 上海长征医院 2022-09-20 CN disclosed
US-20140243363-A1 METHODS AND COMPOSITIONS FOR TREATING ANXIETY DISORDERS OR SYMPTOMS THEREOF PONDERA BIOTECHNOLOGIES INC. (US) 2014-08-28 US disclosed
US-8741319-B2 Methods and compositions for treating anxiety disorders or symptoms thereof Pondera Biotechnologies, Inc. (US) 2014-06-03 US disclosed
US-20140127328-A1 METHODS AND COMPOSITIONS FOR TREATING ANXIETY DISORDERS OR SYMPTOMS THEREOF PONDERA BIOTECHNOLOGIES INC. (US) 2014-05-08 US disclosed
US-5643598-A LIPIDS FOR TREATMENT OF SKIN DISORDERS AS ANTIALLERGENS, ANTIINFLAMMATORY AGENTS OR ANTIAGING COMPOUNDS LVMH RECHERCHE (FR) 1997-07-01 US disclosed
WO-1997000679-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1997-01-09 WO disclosed
US-5443839-A Antiinflammatory, antiallergic and antiaging activity LVMH RECHERCHE (FR) 1995-08-22 US disclosed
EP-0332478-B1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECH (FR) 1992-03-25 EP disclosed
WO-1989008447-A1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECHERCHE (FR) 1989-09-21 WO disclosed
EP-0332478-A1 Liposomes containing Scutellaria extracts LVMH RECHERCHE (FR) 1989-09-13 EP disclosed