Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1773215 | 0.88 | ESR1 (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL13409808 | 0.73 | ALOX15 (0.57) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL10708021 | 0.71 | ESR1 (0.52) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL27896889 | 0.71 | ESR1 (0.52) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL278255 | 0.70 | ESR1 (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL8770754 | 0.69 | ESR1 (0.50) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL28132199 | 0.69 | ESR1 (0.54) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL24115139 | 0.68 | ESR1 (0.48) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL7202909 | 0.68 | ESR1 (0.48) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL19359671 | 0.68 | ESR1 (0.42) | ESR1ESR2CYP3A4LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200362107-A1 | SULFONATED POLY(ARYLENE ETHER) MEMBRANES WITH HIGH MONOVALENT SALT REJECTION EVEN IN THE PRESENCE OF MIXED SALT FEEDS THAT CONTAIN MULTIVALENT SALTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-11-19 | — | — | US | disclosed |