Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22668361 | 0.86 | FFAR1 (0.41) | FFAR1MAOBALOX5ALDH1A1HTT | |
| SCHEMBL22668051 | 0.85 | FFAR1 (0.51) | FFAR1MAOBALOX5ALDH1A1HTT | |
| SCHEMBL22668068 | 0.84 | FFAR1 (0.48) | FFAR1ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL22668106 | 0.81 | MMP9 (0.49) | FFAR1ALOX5 | |
| SCHEMBL22668399 | 0.81 | PPARG (0.57) | FFAR1MAOBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22668115 | 0.81 | FFAR1 (0.46) | FFAR1MAOBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22668393 | 0.80 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL22668082 | 0.80 | FFAR1 (0.51) | FFAR1ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10260737 | 0.80 | MAOB (0.52) | MAOBALOX5ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22668311 | 0.78 | PLA2G4B (0.55) | FFAR1MAOBALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |