Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22668050 | 0.87 | SMN1; SMN2 (0.54) | MAOBSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL434016 | 0.82 | RAB9A (0.49) | MAOBSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL22668372 | 0.80 | FFAR1 (0.47) | MAOBSMN1; SMN2ALDH1A1HTTALOX5 | |
| SCHEMBL432798 | 0.78 | RAB9A (0.58) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL22668051 | 0.78 | FFAR1 (0.51) | MAOBSMN1; SMN2ALDH1A1HTTALOX5 | |
| SCHEMBL16681724 | 0.76 | CHRNB2 (0.53) | SMN1; SMN2MAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL9995389 | 0.76 | CHRNB2 (0.53) | SMN1; SMN2MAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL9787125 | 0.76 | PLA2G4B (0.67) | MAOBSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL434798 | 0.75 | FFAR1 (0.60) | MAOBSMN1; SMN2RAB9AMAPTALDH1A1 | |
| SCHEMBL434797 | 0.75 | FFAR1 (0.60) | MAOBSMN1; SMN2RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |