Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22668386 | 0.90 | RAB9A (0.46) | FFAR1NPC1RAB9ASENP8SENP7 | |
| SCHEMBL15248870 | 0.89 | FFAR1 (0.46) | FFAR1PLA2G4BNPC1RAB9APOLB | |
| SCHEMBL22668329 | 0.88 | FFAR1 (0.46) | FFAR1PLA2G4BNPC1RAB9APOLB | |
| SCHEMBL435299 | 0.88 | FFAR1 (0.55) | FFAR1PLA2G4BNPC1RAB9APOLB | |
| SCHEMBL435298 | 0.88 | FFAR1 (0.55) | FFAR1PLA2G4BNPC1RAB9APOLB | |
| SCHEMBL15239614 | 0.86 | FFAR1 (0.48) | FFAR1PLA2G4BNPC1RAB9APOLB | |
| SCHEMBL15239615 | 0.86 | FFAR1 (0.48) | FFAR1PLA2G4BNPC1RAB9APOLB | |
| SCHEMBL22668438 | 0.86 | PLA2G4B (0.46) | FFAR1PLA2G4BNPC1RAB9APOLB | |
| SCHEMBL22668237 | 0.82 | FFAR1 (0.49) | FFAR1 | |
| SCHEMBL22668392 | 0.81 | RAB9A (0.45) | FFAR1PLA2G4BNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |