Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22668333 | 0.92 | FFAR1 (0.44) | MAPTL3MBTL1LMNAGAAPPARD | |
| SCHEMBL15239180 | 0.89 | FFAR1 (0.51) | MAPTL3MBTL1LMNAMAOBGAA | |
| SCHEMBL10260647 | 0.89 | FFAR1 (0.51) | MAPTL3MBTL1LMNAMAOBGAA | |
| SCHEMBL22668072 | 0.85 | MAPT (0.40) | MAPTL3MBTL1LMNAGAARORC | |
| SCHEMBL22668379 | 0.82 | FFAR1 (0.51) | L3MBTL1MAOBPPARDPPARASMN1; SMN2 | |
| SCHEMBL15239464 | 0.82 | FFAR1 (0.54) | MAPTL3MBTL1GAARORCPPARA | |
| SCHEMBL10260473 | 0.82 | FFAR1 (0.54) | MAPTL3MBTL1GAARORCPPARA | |
| SCHEMBL433532 | 0.76 | ALDH1A1 (0.41) | MAPTL3MBTL1GAACYP3A4POLB | |
| SCHEMBL22668105 | 0.72 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL22668372 | 0.72 | FFAR1 (0.47) | L3MBTL1MAOBSMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |