SCHEMBL2266920

SCHEMBL2266920

CCC=CC=CC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2266917 1.00
SCHEMBL10454308 1.00
SCHEMBL28523515 1.00
SCHEMBL11081284 0.98 ALDH1A1 (0.46)
SCHEMBL26132067 0.91 PPARA (0.52)
SCHEMBL26131411 0.89 ALDH1A1 (0.57)
SCHEMBL26129024 0.82 PPARA (0.71)
SCHEMBL254292 0.81
SCHEMBL30619209 0.81 TRPA1 (0.35)
SCHEMBL400439 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015157500-A1 CLASS IIA HDAC INHIBITORS FOR THE TREATMENT OF INFECTION RESEARCH DEVELOPMENT FOUNDATION (US) 2015-10-15 WO claimed
US-20080219962-A1 Method to Enhance the Bone Formation Activity of Bmp by Runx2 Acetylation BIORUNX CO., LTD. (KR) 2008-09-11 US claimed
EP-1833500-A1 METHOD TO ENHANCE THE BONE FORMATION ACTIVITY OF BMP BY RUNX2 ACETYLATION Biorunx Co., Ltd (KR) 2007-09-19 EP claimed
WO-2006065075-A1 METHOD TO ENHANCE THE BONE FORMATION ACTIVITY OF BMP BY RUNX2 ACETYLATION BIORUNX CO. LTD. (KR) 2006-06-22 WO claimed
EP-0111105-B1 UNSATURATED AROMATIC AMIDES AS PESTICIDES THE WELLCOME FOUNDATION LIMITED (GB) 1990-12-05 EP claimed
EP-3151920-B1 USE OF INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS IN HIV THERAPY SANFORD BURNHAM MED RES INST (US) 2025-08-06 EP disclosed
US-20250213523-A1 COMBINATION OF HDAC INHIBITORS AND STATINS FOR USE IN THE TREATMENT OF PANCREATIC CANCER ISTITUTO NAZIONALE TUMORI IRCCS - FONDAZIONE G. PASCALE (IT) 2025-07-03 US disclosed
US-20250134952-A1 METHODS FOR IMPROVING THE EFFICACY OF HDAC INHIBITOR THERAPY AND PREDICTING THE RESPONSE TO TREATMENT WITH HDAC INHIBITOR Université de Lille (FR) 2025-05-01 US disclosed
EP-4504165-A1 COMBINATION OF HDAC INHIBITORS AND STATINS FOR USE IN THE TREATMENT OF PANCREATIC CANCER Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale (IT) 2025-02-12 EP disclosed
EP-4405680-A1 METHODS FOR IMPROVING THE EFFICACY OF HDAC INHIBITOR THERAPY AND PREDICTING THE RESPONSE TO TREATMENT WITH HDAC INHIBITOR Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2024-07-31 EP disclosed
EP-3594325-B1 METHOD FOR PRODUCING PLATELETS UNIV KYOTO (JP) 2024-07-17 EP disclosed
US-20240191195-A1 METHOD FOR PRODUCING PLATELETS UNIV KYOTO (JP) 2024-06-13 US disclosed
US-20080008810-A1 CONJUGATED DIENAMIDES, METHODS OF PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAME AND USES THEREOF INTERNATIONAL FLAVORS & FRAGRANCES INC. 2008-01-10 US disclosed
EP-1833500-A1 METHOD TO ENHANCE THE BONE FORMATION ACTIVITY OF BMP BY RUNX2 ACETYLATION Biorunx Co., Ltd (KR) 2007-09-19 EP disclosed
WO-2006065075-A1 METHOD TO ENHANCE THE BONE FORMATION ACTIVITY OF BMP BY RUNX2 ACETYLATION BIORUNX CO. LTD. (KR) 2006-06-22 WO disclosed
US-20050075368-A1 Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC.WW 2005-04-07 US disclosed
US-20050074533-A1 Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. 2005-04-07 US disclosed
EP-1520850-A2 Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof INTERNATIONAL FLAVORS &amp; FRAGRANCES INC. (US) 2005-04-06 EP disclosed
CN-1535272-A Nitrogen-containing bicyclic heterocycles ʷ 2004-10-06 CN disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed