Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 11/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 2/20 | 0.39 |
| ▸ | LCLAT1 | Q6UWP7 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294460 | 0.87 | ACSS2 (0.81) | ACSS2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL29433532 | 0.86 | ACSS2 (0.78) | ACSS2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL21305589 | 0.86 | ACSS2 (0.78) | ACSS2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL21294409 | 0.85 | ACSS2 (0.73) | ACSS2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29433482 | 0.85 | ACSS2 (0.73) | ACSS2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29433495 | 0.85 | ACSS2 (1.00) | ACSS2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL21305599 | 0.85 | ACSS2 (1.00) | ACSS2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL21294530 | 0.84 | ACSS2 (0.76) | ACSS2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL21294428 | 0.81 | ACSS2 (0.84) | ACSS2MAPTNPSR1RHOALCLAT1 | |
| SCHEMBL21305672 | 0.81 | ACSS2 (0.86) | ACSS2KDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |