Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 11/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21294409 | 1.00 | ACSS2 (0.73) | ACSS2MEN1POLBKMT2AKDM4E | |
| SCHEMBL29433467 | 0.92 | ACSS2 (0.70) | ACSS2MEN1POLBKMT2ALMNA | |
| SCHEMBL21305733 | 0.92 | ACSS2 (0.70) | ACSS2MEN1POLBKMT2ALMNA | |
| SCHEMBL21305682 | 0.87 | ACSS2 (0.55) | ACSS2MEN1POLBKMT2ALMNA | |
| SCHEMBL29433369 | 0.87 | ACSS2 (0.55) | ACSS2MEN1POLBKMT2ALMNA | |
| SCHEMBL21294460 | 0.86 | ACSS2 (0.81) | ACSS2MEN1POLBKMT2AKDM4E | |
| SCHEMBL22670004 | 0.85 | ACSS2 (0.74) | ACSS2KMT2AKDM4ELMNATSHR | |
| SCHEMBL29433532 | 0.85 | ACSS2 (0.78) | ACSS2KDM4ELMNATSHRNPC1 | |
| SCHEMBL21305589 | 0.85 | ACSS2 (0.78) | ACSS2KDM4ELMNATSHRNPC1 | |
| SCHEMBL21305599 | 0.84 | ACSS2 (1.00) | ACSS2MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566092-B | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |