Sugi Predict

Sugi Predict / Compounds / SCHEMBL2267186

SCHEMBL2267186

SCHEMBL2267186

C=C[Si](CCCC)(c1ccccc1)N(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ OPRM1 P35372 1/20 0.30
▸ OPRL1 P41146 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30
▸ TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2274099 0.85 TSHR (0.33) MEN1KMT2ANPSR1TSHR
SCHEMBL27943213 0.77 NR1H2 (0.33) MEN1KMT2ANPSR1TSHR
SCHEMBL2103061 0.73 TDP1 (0.34) MEN1KMT2ANPSR1OPRM1OPRL1
SCHEMBL2272719 0.73 TDP1 (0.34) MEN1KMT2ANPSR1OPRM1OPRL1
SCHEMBL2291148 0.72 PCSK9 (0.34) TDP1TSHR
SCHEMBL2272329 0.72 THRA (0.33) MEN1KMT2ATSHR
SCHEMBL15302895 0.72 NR1H2 (0.32) MEN1KMT2ANPSR1TSHR
SCHEMBL27604670 0.72 TSHR (0.38) TSHR
SCHEMBL8084574 0.70 KCNH2 (0.36) TDP1TSHR
SCHEMBL2100894 0.70 NPC1 (0.34) NPSR1OPRM1OPRL1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 — — US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 — — US disclosed