Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22672626 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTP53HSD11B1LMNA | |
| SCHEMBL22672637 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTP53HSD11B1LMNA | |
| SCHEMBL22672614 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTP53HSD11B1LMNA | |
| SCHEMBL22672636 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRTP53HSD11B1LMNA | |
| SCHEMBL20844326 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TSHRTP53HSD11B1LMNA | |
| SCHEMBL22672622 | 0.81 | HRH3 (0.51) | ALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL22672734 | 0.81 | HRH3 (0.51) | ALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL3498067 | 0.79 | ATM (0.58) | ALDH1A1LMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL10559542 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRTP53HSD11B1LMNA | |
| SCHEMBL7131881 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRTP53HSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200362339-A1 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS VIA FAST-FLOW SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-11-19 | — | — | US | disclosed |