Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22672734 | 1.00 | HRH3 (0.51) | HRH3ALDH1A1KMT2ATSHRPOLB | |
| SCHEMBL22672626 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL22672637 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL22672636 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL22672614 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL22672732 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL8229259 | 0.80 | ALDH1A1 (0.56) | HRH3ALDH1A1KMT2ATSHRPOLB | |
| SCHEMBL3498067 | 0.79 | ATM (0.58) | ALDH1A1KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL4075003 | 0.77 | ALDH1A1 (0.52) | HRH3ALDH1A1KMT2ATSHRPOLB | |
| SCHEMBL5530068 | 0.77 | ATM (0.60) | ALDH1A1KMT2AKDM4EMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200362339-A1 | PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS VIA FAST-FLOW SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-11-19 | — | — | US | disclosed |