SCHEMBL226728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL226147	0.83	DRD2 (0.52)	DRD2DRD3CA1CA2ACHE
	SCHEMBL2828615	0.81	CA1 (0.47)	DRD2DRD3CA1CA2ACHE
	SCHEMBL226019	0.80	DRD2 (0.49)	DRD2DRD3CA1CA2ACHE
	SCHEMBL224509	0.79	DRD2 (0.50)	DRD2DRD3CA1CA2ACHE
	SCHEMBL227574	0.78	DRD2 (0.50)	DRD2DRD3CA1CA2ACHE
	SCHEMBL4429152	0.78	CA1 (0.49)	DRD2DRD3CA1CA2ACHE
	SCHEMBL227442	0.78	ESR1 (0.54)	DRD2DRD3CA1CA2ACHE
	SCHEMBL223786	0.78	CA1 (0.44)	DRD2DRD3CA1CA2ACHE
	SCHEMBL225574	0.78	ESR1 (0.61)	DRD2DRD3CA1CA2ACHE
	SCHEMBL229270	0.78	DRD2 (0.47)	DRD2DRD3CA1CA2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.