Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414605 | 0.69 | UTS2R (0.42) | MTNR1AMTNR1BCCNKCDK12 | |
| SCHEMBL20536455 | 0.68 | PDK2 (0.38) | ADORA1ADORA2AALDH1A1CCNKCDK12 | |
| SCHEMBL10223044 | 0.66 | BRD4 (0.46) | FGFR1FGFR2KITMAP3K11DYRK1A | |
| SCHEMBL15618545 | 0.65 | ADORA1 (0.42) | ADORA1ADORA2ACCNKCDK12KDM4E | |
| SCHEMBL2156821 | 0.64 | MTNR1A (0.64) | MTNR1AMTNR1BPOLBKDM4EMAPT | |
| SCHEMBL16065332 | 0.62 | MTNR1A (0.45) | PDE3BPDE3AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL25153355 | 0.60 | CHEK1 (0.37) | ALDH1A1KDM4ELMNAMAPTFGFR1 | |
| SCHEMBL30280429 | 0.60 | CHEK1 (0.37) | ALDH1A1KDM4ELMNAMAPTFGFR1 | |
| SCHEMBL30280430 | 0.60 | CHEK1 (0.37) | ALDH1A1KDM4ELMNAMAPTFGFR1 | |
| SCHEMBL24541944 | 0.60 | ADORA1 (0.43) | ADORA1ADORA2AALDH1A1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232470-A1 | CHEMICAL COMPOUNDS | Boragen, Inc. (US) | 2020-11-19 | — | — | WO | disclosed |