SCHEMBL2267459

SCHEMBL2267459

Cn1ccn(C)c1=N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21859332 0.73 TYR (0.33)
SCHEMBL21859333 0.69 INMT (0.40)
SCHEMBL16532135 0.61 LPO (0.44)
SCHEMBL32676509 0.59 LPO (0.42)
Hydrochloric Acid SCHEMBL7535543 0.57 LPO (0.40)
SCHEMBL4228193 0.56
SCHEMBL32676586 0.56 LPO (0.38)
SCHEMBL31491268 0.56
SCHEMBL21387937 0.50 PIK3CD (0.33)
SCHEMBL18773169 0.49

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023091644-A2 HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-05-25 WO disclosed
US-20230012362-A1 WDR5 INHIBITORS AND MODULATORS VANDERBILT UNIVERSITY 2023-01-12 US disclosed
WO-2020247679-A1 WDR5 INHIBITORS AND MODULATORS VANDERBILT UNIVERSITY (US) 2020-12-10 WO disclosed
US-9593080-B1 Triazabutadienes as cleavable cross-linkers THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-03-14 US disclosed
EP-2219590-B1 COMPOSITION FOR OXIDATION DYEING OF HUMAN KERATIN FIBRES AT A PH OF LESS THAN 8, COMPRISING A FATTY ALCOHOL, A FATTY ESTER AND A CATIONIC SURFACTANT, METHOD USING SAME AND DEVICE ORÉAL L (FR) 2015-03-11 EP disclosed
EP-2643332-B1 METHOD FOR BUFFERING A CHEMICAL OR BIOLOGICAL COMPOSITION SACHEM INC (US) 2014-10-22 EP disclosed
EP-2643332-A2 METHOD FOR BUFFERING A CHEMICAL OR BIOLOGICAL COMPOSITION Sachem, Inc. (US) 2013-10-02 EP disclosed
US-8361779-B2 Buffer compounds SACHEM, INC. (US) 2013-01-29 US disclosed
WO-2012071102-A2 BUFFER COMPOUNDS SACHEM, INC. (US) 2012-05-31 WO disclosed
US-20120129240-A1 BUFFER COMPOUNDS SACHEM, INC. 2012-05-24 US disclosed
EP-2383252-A1 METHOD FOR MANUFACTURING HYDROXYL GROUP SUBSTITUTION PRODUCT Central Glass Company, Limited (JP) 2011-11-02 EP disclosed
US-20110251403-A1 Method for Manufacturing Hydroxyl Group Substitution Product CENTRAL GLASS COMPANY, LIMITED (JP) 2011-10-13 US disclosed
US-20110173807-A1 DISPERSION FOR DISPOSING FINE PARTICLE AT PREDETERMINED POINT ON SUBSTRATE BY INK-JET PRINTING NATOCO CO., LTD. (JP) 2011-07-21 US disclosed
US-6998050-B2 Method of treating fats and oils KABUSHIKI KAISHA TOSHIBA (JP) 2006-02-14 US disclosed
US-20030175401-A1 Method of treating fats and oils KABUSHIKI KAISHA TOSHIBA (JP) 2003-09-18 US disclosed
EP-1332774-A2 Method of treating fats and oils Kabushiki Kaisha Toshiba (JP) 2003-08-06 EP disclosed