Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GRB2 | P62993 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627659 | 0.85 | LCK (0.51) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL29592816 | 0.85 | LCK (0.66) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL259612 | 0.85 | LCK (0.66) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL259330 | 0.84 | KDM4E (0.50) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL2627650 | 0.82 | KDM4E (0.50) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL10065007 | 0.81 | KDM4E (0.45) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL6689431 | 0.81 | HSD17B3 (0.62) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL15984343 | 0.80 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL24623285 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL22871876 | 0.80 | KDM4E (0.74) | ALDH1A1KDM4EHPGDLMNALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279733-B2 | Peptide antibiotics | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-03-22 | — | — | US | disclosed |
| US-20200361994-A1 | PEPTIDE ANTIBIOTICS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361994-A1 | PEPTIDE ANTIBIOTICS | NGLY1, VIP, PEPD | ALDH1A1 4862/4885KDM4E 4639/4885HPGD 3755/4885 |
| US-11279733-B2 | Peptide antibiotics | NGLY1, VIP, PEPD | ALDH1A1 4862/4885KDM4E 4639/4885HPGD 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.