Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22632228 | 0.87 | MTNR1A (0.58) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL24623284 | 0.84 | SLC18A1 (0.48) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL24623256 | 0.83 | IGLV6-57 (0.46) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL24623269 | 0.82 | RAD52 (0.45) | ALDH1A1KDM4EHPGDPOLBMTNR1A | |
| SCHEMBL24623214 | 0.82 | MTNR1A (0.64) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL22632229 | 0.82 | SLC18A1 (0.50) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL22677549 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL24623270 | 0.78 | DRD4 (0.45) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL24623218 | 0.77 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDNPC1POLB | |
| SCHEMBL2633118 | 0.76 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218722-A1 | COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218722-A1 | COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER | AR, SHBG, NCOA1 | ALDH1A1 1280/4885KDM4E 4644/4885HPGD 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.