Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22678226 | 0.86 | IKBKB (0.37) | SMN1; SMN2RAB9ANPC1TP53MITF | |
| SCHEMBL17385341 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL22677789 | 0.81 | TP53 (0.41) | SMN1; SMN2RAB9ANPC1TP53MITF | |
| SCHEMBL22678180 | 0.81 | CYP2A6 (0.33) | SMN1; SMN2RAB9ANPC1TP53MITF | |
| SCHEMBL22677937 | 0.78 | CRBN (0.36) | SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL22677989 | 0.77 | HRH4 (0.39) | SMN1; SMN2RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL22678205 | 0.76 | RAB9A (0.45) | RAB9ANPC1TP53MAPTLMNA | |
| SCHEMBL22678287 | 0.75 | STAT3 (0.46) | SMN1; SMN2TP53MAPTMGLLLMNA | |
| SCHEMBL22677996 | 0.75 | RPS6KB1 (0.39) | SMN1; SMN2RAB9ANPC1TP53MGLL | |
| SCHEMBL22678636 | 0.74 | PPARG (0.41) | SMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157904-B1 | ANTI-INFECTIVE COMPOUNDS | PASTEUR INSTITUT KOREA (KR) | 2020-11-18 | — | — | EP | disclosed |