Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10222485 | 0.82 | UHRF1 (0.43) | UHRF1CYP1A2CYP2A6NOS3NOS1 | |
| SCHEMBL21711087 | 0.72 | UHRF1 (0.35) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL12848758 | 0.72 | UHRF1 (0.41) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL27334254 | 0.71 | UHRF1 (0.34) | UHRF1 | |
| SCHEMBL2611021 | 0.70 | UHRF1 (0.50) | UHRF1CYP1A2CYP2A6 | |
| SCHEMBL138354 | 0.68 | — | — | |
| SCHEMBL29503884 | 0.68 | — | — | |
| SCHEMBL24220127 | 0.67 | NOS3 (0.43) | NOS3NOS1NOS2 | |
| SCHEMBL18594716 | 0.65 | — | — | |
| SCHEMBL22299273 | 0.65 | LMNA (0.39) | UHRF1CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3412660-B1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | EA PHARMA CO LTD (JP) | 2020-11-18 | — | — | EP | disclosed |